Saturday, December 8, 2018

Chinese Medicine used to Treat Food Allergies



During a group hike today, a young lady and schoolmate mentioned her food allergy history. While off the top of my head I recommended trying out jujube as a dietary ingredient, I decided that this is a topic that worth a better account and understanding from a holistic medicine perspective.

Allergy was a relatively distant concept when I was growing up, but with more modern developments in all areas of our lives, from genetically modified plants to new chemical materials, skin allergies and seasonal allergies seemed to become so prevalent nowadays and with the communication of goods across the global village, it is no longer a regional problem. Over the recent years, I heard friends telling me about their food allergy to seafoods, peanuts, fruits, and so on. Not surprising, I was recently tested allergic reaction in the middle of acute cough – it was expected based on my understanding of Traditional Chinese Medicine (TCM), but the same results might create false alerts or unnecessary panic to some folks who do not understand it.

People suffering from food allergies aren’t always aware that their symptoms are caused by the food they are eating. It often can be more difficult to discover that a person is allergic to a certain type of food, as opposed to discovering that a person is allergic to a bee sting, for example. Some people suffering from food allergies continue their day-to-day life with symptoms such as headaches or fatigue and have no idea that their symptoms could be from food allergies.


Symptoms of food allergies include: fatigue, hives, eczema, abdominal pain, diarrhea, nausea, vomiting, nasal congestion, cough and asthma. Even more serious conditions include: difficulty breathing, decreased blood pressure, increased heart rate, dizziness, mental confusion, slurred speech, anxiety attack and cardiovascular collapse, according to the American Academy of Acupuncture and Oriental Medicine (AAAOM).

Many herbalists consider two major systems when dealing with allergies – the immune system and adrenal-stress handling system. These two systems are under great pressure due to environmental changes. The fast pace of modern living and working may have an adverse effect on these systems, as well.

There are many natural ways to nourish the immune system and lessen the impact of stress on the body’s systems: meditation, walking, breathing exercises, a diet of whole, organic foods and a network of loving relationships.

Traditional Chinese Medicine, one of the oldest medical practices in the world, which has benefited patients for several thousands of years in China, 1500+ years for patients in Japan and 1300 years in Korea, is focused on finding the source of the problem and treating the underlying imbalance that produces the symptoms of the food allergy. It can reduce the body’s negative reaction to foods, support the functioning of the internal organs and improve the immune system.

A study published in 2002 reported a 95% effective rate when using Chinese medicine to treat 20 patients suffering from food allergies. The patients, all between six and 67 years old, complained of food allergy gastritis after eating certain food. They were each given a daily formula consisting of prepared Chinese herbs. In result, 14 patients were considered cured, and five patients improved.

During another study conducted in the US in 2014, an herbal formula using mixture of herbs described in TCM herbal classics has shown to be highly effective in providing long-term protection against peanut-induced anaphylaxis, with a high safety margin. Other TCMs also show a potential for treating food allergies in preclinical studies.


Wu Mei Wan, or Mume Pills, classical 10-herb formula, was the basis for the development of an herbal formula for food allergies. This formula is known to effectively treat intestinal parasite infections and gastrointestinal disorders with symptoms similar to food allergy and gastroenteritis.



Ling Zhi (Ganoderma Lucidum), a herb known to have significant anti-inflammatory and anti-allergy effects, was added, and this 11-herb formula was named food allergy herbal formula-1 (FAHF-1).
Subsequently, two herbs (Xi Xin [Herba cum radice asari] and Zhi Fu Zi [Radix lateralis aconiti carmichaeli praeparata]) that may be potentially toxic if improperly processed were removed. This final 9-herb formula was named food allergy herbal formula-2 (FAHF-2); the herbal constituents are shown in Table 1 below.


Although FAHF-2 is called a new herbal name, all herbs in it have a long history of human use and are widely used today in China, Japan, and Korea and are also currently marketed in the United States. Clinical studies have demonstrated the beneficial effects of Wu Mei Wan with or without modification on various diseases, including gastroenteritis and asthma, and no adverse effects were reported. Ling Zhi has been shown to be beneficial for several chronic inflammatory conditions, including chronic bronchitis, bronchial asthma, and allergic rhinitis.

Other Preclinical Studies of Potential Herbal Medicine Therapies for Food Allergy

Kakkonto

Kakkonto is a Japanese-Chinese herbal formula composed of seven medicinal plants (based on Kampo medicine). Yamamoto et al. tested the effect of kakkonto in a murine model of food allergy (ovalbumin [OVA]) with gastrointestinal symptoms. Kakkonto treated mice had a significant reduction in OVA-induced diarrhea. Although no difference in OVA-specific IgE levels were observed between mice receiving kakkonto and untreated mice, the number of mucosal mast cells was reduced in the proximal colons of mice that received kakkonto.

Qian Cao (Rubia cordifolia) and Qu Mai (Dianthus superbus) Extracts

Seventy herbal extracts were tested for their ability to reduce IgE secretion by the human B-cell line (U266). 

Rubia cordifolia and Dianthus superbus extracts potently inhibited IgE production in vitro in a non-toxic manner. Potential effects of both extracts were then tested in a murine model of peanut-induced anaphylaxis. Both extracts reduced peanut-specific IgE levels in a dose-dependent manner, but not peanut specific IgG1 levels. Rubia cordifolia and Dianthus superbus treated mice also exhibited significantly lower anaphylaxis symptom scores and reduced plasma histamine levels following peanut challenge.

Chinese medicine sees the body as interacting organ systems, and also as a system of energy pathways that connect all parts of the body. Deficiencies or disharmonies in the organs can be the basis of multiple food allergies.

The most obvious way to avoid an allergic reaction to food would be to take that type of food out of a person’s diet.  But, if a person is allergic to many different kinds of foods, it can be impossible to stop eating everything he or she is allergic to. Therefore, the Chinese medicine approach is to make it possible for the body to respond normally to these foods instead of completely cutting these foods out of a person’s diet. According to a practitioner and professor of Allergy and Immunology at Mount Sinai Medical Center, most food allergic patients are asymptomatic, averaging fewer than one accidental reaction per year.

A Chinese medicine practitioner will select acupuncture points and herbal formulas that support the functioning of the organs, dispersing unhealthy excess patterns and nourishing deficiencies. Chinese medicine is a safe and effective way of treating food allergies. We will touch on TCM view and treatments for other kinds of allergies in the future blog posts.

References:


Allergy Treatment Spotlight: Chinese Herbal Allergy Remedies https://foodallergycanada.ca/2017/11/allergy-treatment-spotlight-chinese-herbal-allergy-remedies/

Bensky D, Gamble A. Materia medica. Seattle: Eastland Press; 1993. Chinese herbal medicine.
Chinese Herbal Therapy for the Treatment of Food Allergy https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276304/
www.nccam.nih.gov/health/backgrounds/wholemed.htm
Chinese Herbal Medicine for the Treatment of Allergic Diseases
Chinese Herbal Medicine to Treat Allergic Rhinitis: Evidence from a Meta-Analysis https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705481/

Chinese medicine used to treat food allergies https://www.pacificcollege.edu/news/blog/2014/07/08/chinese-medicine-used-treat-food-allergies


Excuse Me, Is this Allergen Free

https://www.slideshare.net/NCANA/excuse-me-is-this-allergen-free

He FH, Wu WP. Clinical application of Wu-Mei-Wan. Zhong Gui Yi Yao Xue Ba. 2004;19:748–50.


Hu KM, He YM. Correlation between complex prescription with lucidum ganoderma in treating rhinoallergitus and constitution. Shanghai J Trad Chinese Med. 2000;8:39–41.

Huang KC. The pharmacology of Chinese herbs. 2. Boca Raton: CRC Press; 1999. pp. 118–20.

Lopez-Exposito I, Castillo A, Yang N, et al. Chinese herbal extracts of Rubia cordifolia and Dianthus superbus suppress IgE production and prevent peanut-induced anaphylaxis. Chin Med. 2011;6:35.[PMC free article] [PubMed]

Tasaka K, Akagi M, Miyoshi K, et al. Anti-allergic constituents in the culture medium of Ganoderma lucidum. (I). Inhibitory effect of oleic acid on histamine release. Agents Actions. 1988;23:153–6. [PubMed]

Wen MC, Teper A, Srivistava KD, et al. Immunology of T cells by the Chinese herbal medicine Ling Zhi (gandoderma lucidum) J Allergy Clin Immunol. 2003;111:S320.

Wind Dispersing Powder. http://www.shen-nong.com/eng/exam/formulai1.html

Yamamoto T, Fujiwara K, Yoshida M, et al. Therapeutic effect of kakkonto in a mouse model of food allergy with gastrointestinal symptoms. Int Arch Allergy Immunol. 2009;148:175–85. [PubMed]

Zhang Xin-Cheng, et al. Xin Zhong Yi. #9 pp. 59-60. 2002

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